The team that won the last six series between the division rivals went on to reach the NBA Finals, winning four.
James had 22 points and is fifth on the NBA’s all-time list for triple-doubles.
Stephen Curry scored 27 points to lead the Warriors, who were coming off an impressive home win over the Utah Jazz a day earlier but suffered their fifth loss in six games.
The Lakers (26-13) are narrowly behind the Phoenix Suns near the top of the Pacific division while the Warriors are 20-20 and the Jazz have the NBA’s best record of 28-10.
The in-form Suns improved to 26-12 with Devin Booker scoring 27 points as Phoenix rolled to a 122-99 victory over the visiting Memphis Grizzlies.